Joe Gardner is a middle-school band teacher who gets the chance of a lifetime to play at the best jazz club in town. A misstep takes him from New York City to The Great Before, a fantastical place where new souls get their personalities before going to Earth. Determined to return to his life, Joe teams up with a precocious soul, 22, who has never understood the appeal of the human life. As Joe tries to show 22 what's great about life, he may discover...

Outside Covent Garden on a rainy evening in 1912, cockney flower girl, Eliza Doolittle, meets linguistic expert Henry Higgins. Higgins, in turn, bets with his companion, Colonel Pickering, that, within six months, he could transform Eliza into a proper lady, simply by teaching her proper English. The next morning, face and hands freshly scrubbed, Eliza presents herself on Higgins' doorstep, ready and willing to be turned into a lady.