Callie rides an emotional roller coaster while serving on the stage crew for a middle school production of Moon over Mississippi as various relationships start and end, and others never quite get going

Ten-year-old Auggie Pullman, who was born with extreme facial abnormalities and was not expected to survive, goes from being home-schooled to entering fifth grade at a private middle school in Manhattan, which entails enduring the taunting and fear of his classmates as he struggles to be seen as just another student.

Chase does not remember falling off the roof, in fact he does not remember anything about himself, and when he gets back to middle school he begins to learn who he was through the reactions of the other kids--trouble is, he really is not sure he likes the Chase that is being revealed, but can he take the opportunity amnesia has provided and restart his life?

Nate goes up against Gina, the class brainiac.

"Big Nate is in a class by himself! An irrepressible sixth grader with plenty of confidence. Nate's blazing a trail through middle school that his teachers and classmates won't soon forget. And even if that trail usually leads straight to detention...well, there's no denying that Nate gets there in style. Whether he's taking one of Mrs. Godfrey's notorious pop quizzes, trading barbs with grade-grubbing Gina, or starting the world's greatest garage...

As one of the only Asian Americans in her school, Christina confronts both well-meaning ignorance and cruel racism, but in middle school fitting in is important, which is why she and her best friend Megan are both excited and nervous to try out for the popular cheerleading squad.

After being diagnosed with a rare eye cancer, twelve-year-old Ross discovers how music, art, and true friends can push him through treatment and survive middle school.

"Link, Michael, and Dana live in a quiet town. But it's woken up very quickly when someone sneaks into school and vandalizes it with a swastika. Nobody can believe it. How could such a symbol of hate end up in the middle of their school? Who would do such a thing? Because Michael was the first person to see it, he's the first suspect. Because Link is one of the most popular guys in school, everyone's looking to him to figure it out. And because Dana's...

After his fight with Randy Betancourt makes headlines in the school paper, Big Nate has a problem worse than detention on his hands.

Told in alternating voices, the teacher and students in room 117 find their lives changed over the course of a school year.